This document provides policymakers with a list of ‘best buys’ and other recommended interventions to address noncommunicable diseases (NCDs) based on an update of Appendix 3 of the Global Action Plan for the Prevention and Control of NCDs 2013–2020. A list of options is presented for each of the four key risk factors for NCDs (tobacco, harmful use of alcohol, unhealthy diet and physical inactivity) and for four disease areas (cardiovascular disease, diabetes, cancer and chronic respiratory disease).